Sigenics biomedical expertise is in neural signal acquisition and neural stimulators. We also have extensive experience in electrode chemistry and magnetic telemetry systems. Many of our devices are passive and wireless, using a magnetic field to both power and control the implanted device. We have developed systems for NIH and DARPA grant programs as well as medical devices for commercial customers. Some example projects are briefly described below:
Implantable MyoElectric sensor, or “IMES”
A Sigenics implanted device sends EMG (muscle) signals to an outside controller which controls motors in a prosthetic limb. A collection of the sensors are implanted directly next to the muscles so that they sense the muscle contractions and send a radio signal to the external controller, which uses the information to control the prosthetic. This device is now in human clinical trials.
Board-level controller with DSP to drive motors in a prosthetic limb
This external controller uses IMES data to drive the motors in the prosthesis. The end result is to create more natural prostheses that move with more degrees of freedom and are controlled by the signals from the user’s muscles.
Cortical visual prosthesis
Video from an external camera is processed to produce a series of stimulation commands. These commands are sent wirelessly to an implanted device which stimulates electrodes inserted into the visual cortex of the brain to create the perception of spots of light, which are perceived by the user as an image.
This is another type of visual prosthesis. Electrical impulses directly stimulate nerves in the retina, bypassing the need for photoreceptors to produce images. Applications include improving the vision of those affected by macular degeneration.
Implantable nerve stimulator for cluster headache treatment
The small wireless device is implanted under the cheekbone to stimulate the trigeminal nerve and eliminate or drastically reduce migraine headaches, and is now in human clinical trials.
Board-level electrocautery device
The device contains Sigenics’ ASICs to seal varicose veins using a high energy electrical impulse.
EKG (electrocardiogram) signal processing front end ASIC
The implanted chip amplifies and processes the heart’s electrical signals to detect potentially harmful fibrillations.
DNA microarray chip
A sample on a piece of silicon “litmus paper” containing up to 100,000 different desired DNA sequences is applied to the surface of the chip, and the DNA sequences of the sample that match the sequences on the chip are detected. This allows specific DNA sequences to be determined in patients.
Designed specifically to support Sigenics’ biotelemetry research, this 65-kilohertz tuned RF receiver chip accepts backscatter telemetry from Sigenics’ implanted devices. Applications include implantable EMG sensors, wireless EKGs, and passive or active RFID tag read front ends.
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